The PLK1 gene you inquire is
evaluated as high risk to knockout in cell line.
Gene lethality scoreData are derived from the results of genome-wide CRISPR library screening
Lethality score of PLK1 in different cells
All cells
99.7%>0.5
Non-essential gene: 0
Boundary score: 0.5
Essestial gene: 1
The higher the score, the higher the dependence of gene on the
cell line. If the score is >0.5, it is defined that there is a lethality
risk after gene knockout.
Related products in Ubigene
Gene Knockout kit
EZ-editor™Gene Knockout kit
All-in-one solution for efficient and convenient construction
The data comes from the Red Cotton Knockout Project ▪ KO cell line bank project
Successfully implemented
We have successfully knocked out this gene in cells.
Likely to fail
We have made attempts to knock out this gene, but the projects were
either not that successful or failed, indicating that this gene knockout
is risky.
No Record
We haven’t applied knockout on this gene.
Note:
This result refers to two data, gene lethality score and project implementation risk. Due to
the uncertainty of scientific experiments, different cell sources and different operations
may lead to different results, so the above assessment is for reference only.
